“Though the Witch knew the Deep Magic, there is a magic deeper still which she did not know. Her knowledge goes back only to the dawn of time. But if she could have looked a little further back… she would have known that when a willing victim who had committed no treachery was killed in a traitor’s stead, the Table would crack and Death itself would start working backward.” - Aslan, C.S. Lewis, The Lion, the Witch and the Wardrobe

SWANK Profile: Ketoconazole

SWANK Profile: Ketoconazole

The Heavy Hitter. The Endgame Burner.

Filed Under: Liver Watch / Fat-Soluble Fungus / Hormonal Interference Recovery


1. Broad-Spectrum Antifungal

Ketoconazole is potent against:

  1. Candida
  2. Tinea (ringworm, jock itch, athlete’s foot)
  3. Seborrheic dermatitis + dandruff
  4. Histoplasma, blastomyces, and other deep fungi
  5. Skin + mucosal colonization
  6. Mild efficacy against mold in tissues and fat

Used when fungus has spread but isn’t responding to lighter meds.


2. Targets Fungus in Hormone-Sensitive Tissue

Ketoconazole also inhibits:

  1. Steroid synthesis in the adrenal glands
  2. Cortisol + testosterone production (dose-dependent)

It’s sometimes used in Cushing’s Syndrome and prostate cancer.

But in fungal purging, this means:

Be cautious if you’re hormonally sensitive—support adrenals (licorice root, vitamin C, adaptogens) if needed.


3. Fat-Bound Fungus + Sebaceous Tissue

Excellent for:

  1. Scalp
  2. Face
  3. Upper chest + back
  4. Hair follicles + oil glands

Especially in:

  1. Seborrheic dermatitis
  2. Fungal acne
  3. Chronic oily skin + fungal inflammation


4. Works Where Skin Meets Endocrine

Some call Ketoconazole the “hormone-aware antifungal.”

It acts on tissue systems where fungus and hormone disruption overlap:

  1. Skin
  2. Scalp
  3. Fatty lymph areas
  4. Adrenals
  5. Cortisol-regulating zones

Often used topically, but oral dosing penetrates far deeper.


Mechanism of Action:

  1. Blocks 14α-demethylase → disrupts ergosterol synthesis
  2. Interferes with fungal cell membranes
  3. At higher doses: inhibits adrenal steroidogenesis


Dosing (Oral):

  1. 200mg every other day or every third day x 21–30 days MAX
  2. Must be taken with food and acid (no antacids)


Cautions:

  1. Liver support required (watch ALT/AST if long-term)
  2. Avoid alcohol and other hepatotoxic meds during cycle
  3. Watch energy and mood if adrenals are fragile


Notable Benefits:

  1. Clears skin + facial fungus deeply and quickly
  2. Resets oily fungal terrain
  3. Temporarily lowers cortisol if chronically high
  4. Often last-resort option after Fluconazole and Itraconazole


What It Doesn’t Do:

  1. Doesn’t rebuild terrain
  2. Doesn’t kill gut-only candida (combine with Nystatin if needed)
  3. Not ideal for long-term unless clinically monitored


Conclusion:

Ketoconazole is your controlled burn.

It doesn’t come first—but when the colonists won’t leave, and your face, scalp, and endocrine tissue are under siege, it wipes them out fast.

Use it short-term. Pair with support.

It’s not a supplement—it’s fungal fi

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