SWANK Dispatch: Gut Bacteria Make Your Neurotransmitters
Mood, Mind, and Microbiome Are Not Separate Things
Filed Under: Neuro-Gastro Harmony / Microbial Signaling / Emotional Terrain
What This Means:
The microbes in your gut—especially beneficial bacteria—literally manufacture the chemical messengers that control your:
- Mood
- Sleep
- Focus
- Motivation
- Stress response
- Emotional resilience
These messengers are called neurotransmitters.
Which Gut Bacteria Make What?
1. Serotonin
- ~90% of your serotonin is made in the gut
- Used for mood, calm, digestion, and sleep
- Made by Lactobacillus, Bifidobacterium, and other commensals
If your gut is inflamed or overrun with fungus, serotonin production plummets.
2. GABA (Gamma-Aminobutyric Acid)
- Your main calming neurotransmitter
- Reduces anxiety, slows racing thoughts, lowers blood pressure
- Produced by certain strains of Lactobacillus rhamnosus and others
Gut imbalance = no brakes on stress = panic, insomnia, tension.
3. Dopamine
- Controls pleasure, motivation, and reward
- Gut bacteria create precursors to dopamine
- Healthy microbes help convert tyrosine and phenylalanine into usable signals
Dysbiosis = brain fog, apathy, depression, lack of drive
4. Norepinephrine & Epinephrine
- Regulate alertness, fight-or-flight, and blood sugar
- Produced in part by gut-enteric signaling—bacteria help modulate release
5. Acetylcholine
- Essential for memory, cognition, and muscle movement
- Gut bacteria assist in choline metabolism and neuroplasticity signaling
How Do Gut Bacteria Do This?
- They break down food into amino acids + metabolites
- They ferment fiber into short-chain fatty acids (SCFAs), which regulate brain inflammation
- They signal the vagus nerve, which connects gut to brain like a psychic USB port
- They influence gene expression that determines how neurotransmitters are used
Why It Matters:
If your gut microbiome is:
- Fungal-dominant
- Antibiotic-wrecked
- Sugar-fed
- Inflamed
- Missing key bacterial species
Then your neurotransmitter system is misfiring.
You don’t feel bad because you’re broken.
You feel bad because your neurochemical assembly line is out of workers.
Conclusion:
Gut bacteria don’t “help” your brain.
They build your mood chemistry from scratch.
You’re not emotionally unstable.
You’re microbially understaffed.
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